Everyday pain management ideas

I remember working in retail pharmacy in the 1980s and 1990s when NSAIDs were all the rage. This class of drugs was one of the most commonly prescribed.  As the years went on, we all became aware of the problems associated with this class of drugs.  The first problem that became obvious was that patients who used these drugs on a regular basis were developing gastric ulcers and GI bleeding. For that reason, it was advised that these medications be taken with food.  One company even developed an NSAID product that contained an additional drug that was purported to protect the lining of the GI tract from injury. After this era, a new sub-class of these drugs--known as "COX-2" inhibitors came onto the US marketplace. This class of drugs possesses all the benefits of the original NSAID drugs--but did not have the GI side effects of the original NSAID drugs.  Three COX-2 Inhibitors (Bextra®, Vioxx®, and Celebrex®) were launched in the US market in the late 1990s-e...

I have been a migraine headache sufferer for most of my adult life.  It always seemed like when I had a day off of work, or a day where I could simply relax, I could not really do so because that's when I was most apt to have a migraine.  Now if that doesn't stink to high heaven, I don't know what does... An article from March of 2014 has recently helped me to understand why this has been the case.  A study conducted at Yeshiva University concluded that persistent stress followed by relaxation is actually a trigger for migraine headache. The study authors came to this conclusion after examining headache diaries of migraine patients. According to study authors, this finding emphasizes the importance of stress reduction and healthy lifestyle habits for migraine sufferers. In the US there are reported to be 37 million migraine sufferers,  of which almost 5 million experience attacks at least once monthly.  More women are affected than men, and the average ...

New research into a group of compounds known as endomorphins may offer hope to chronic pain patients of the future.  These compounds are based on endorphins, which are the human body's naturally occurring pain relievers.  Researchers say that these compounds appear to be superior to morphine in terms of analgesia, and have fewer side effects as well.  The other big advantage to these compounds is that there appears to be no risk of addiction, respiratory depression, constipation, and some of the other problems that develop with the use of opioids.  This would be a most wonderful development in the world of pain management! Endorphin molecule In the meantime, one of the best ways to help your body deal with chronic pain is to practice activities that help to increase natural endorphin levels.  According to Reader's Digest , here are eight ways to reach this goal: The scent of vanilla and lavender are said to increase endorphin levels.  T...

Spinal cord stimulators (SCS) have been a part of the pain management marketplace for a very long time. These devices are all basically the same; they are electrodes, surgically implanted in the epidural space of the spine.  These electrodes are attached to an impulse generator which is implanted in the abdomen or gluteus.  The other key piece of the system is a remote control which is used to modify the the electrical signals being transmitted to the spinal cord via the electrodes.  These electrical signals become "white noise" to the nervous system in an effort to "scramble" the pain signals, making pain more bearable for the patient.. The goal here is to maximize the patient's comfort while minimizing dependency on pain medication. These devices are most commonly used for patients with failed back surgeries, who really have no alternative but to find ways to cope with chronic pain. Electrode Placement Example--Spinal Cord Stimulator Up until rece...

Today I am sharing an article about one multi-modal approach to chronic pain that makes a lot of sense to me... I don't want to elaborate too much because I think it's worth it for you to read for yourself.  All I can say in advance is that this article makes me think of a three-legged stool.  If you only rely on one leg of the stool, it's certainly not going to be very useful. So without further ado, here is a link to the article I am speaking of.  Read and contemplate...comments are appreciated! Sources: statnews.com; wikimedia

Rheumatoid Arthritis (RA) is a progressive, painful crippling disease. It's unfortunately a common condition, and RA patients comprise a large segment of the chronic pain population. Fortunately, for the most part, the current standards of treatment for this condition do NOT include the use of opioids. A recent study published in Arthritis & Rheumatology examined chronic opioid usage in almost 14,000 RA patients over a fourteen year period.  Surprisingly, when the patients in the study were using chronic opioids, they had a significant increase in rate of infection.  The study authors found a twofold risk of infection in opioid vs. non-opioid populations. Why is this so?  In vitro studies have shown that certain opioids--morphine, methadone, and fentanyl--have immune suppressive properties. This can be attributed to inhibition of T-cell receptor signaling, reductions in natural killer cell activity, and depletion of lymphocytes, according to said studies. ...

Pain management is a complicated field.  For one thing, there is an objective goal--that is to say, to determine what is causing pain in the first place, and what to do about it. But we also have to consider subjective aspect of pain management.  One of the tenets of pain management is this: If a person says they are in pain, we cannot deny that the pain exists.  But sometimes it's hard to determine why that person is experiencing this discomfort, or why it seems to be as severe as they claim. In recent years the genetic aspect of pain management is under closer study.  One example of this is a group from Touro College of Pharmacy in New York City.  Dr. Priyank Kumar and his associates are looking at a specific human gene--namely, 118G. They are finding that variations in this particular gene help to predict a patient's response to opioids, and also the risk of respiratory depression, opioid misuse and even addiction. Genetic testing of this sort may...